Midwifery: best practice. Mother with anti-Kell antibodies. What are the recommendations for managing patients with anti Kell antibodies? I have a pregnant patient with anti-Kell antibodies (titer is 1:4). What are the recommendations for managing patients with anti Kell antibodies? The American College of Obstetricians and Gynecologists recommends determination of the father’s red blood cell antigen status as the first step. To determine the father's Kell antigen status most laboratories will ask that you submit 5 mL of the father’s blood drawn into a Lavender-top (EDTA) tube with a request to perform Red Blood Cell Antigen Typing, Kell antigen, Kell blood group phenotype on the father’s blood. If the father is negative for the Kell antigen (and it is certain that he is the father of the fetus) further evaluation is unnecessary.
Serial antibody titers are commonly used for monitoring fetal status with a first sensitized pregnancy in Rh disease. The peak systolic velocity is measured in the MCA closest to the transducer when the fetus is not active or breathing. REFERENCES 1.McKenna DS, et al. 2. 4. 5. 6. 7.